{"id":5783,"date":"2017-11-24T11:51:36","date_gmt":"2017-11-24T02:51:36","guid":{"rendered":"http:\/\/www.successgroup.cc\/blog\/?p=5783"},"modified":"2017-11-24T11:51:36","modified_gmt":"2017-11-24T02:51:36","slug":"%e3%82%b5%e3%82%a4%e3%83%90%e3%83%bc%e3%83%9e%e3%83%b3%e3%83%87%e3%83%bc%e3%81%af%e6%9d%a5%e9%80%b1%ef%bc%92%ef%bc%97%e6%97%a5%e6%9c%88%e6%9b%9c%e6%97%a5%e3%81%a7%e3%81%99%ef%bc%81%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.successgroup.cc\/blog\/5783\/%20","title":{"rendered":"\u30b5\u30a4\u30d0\u30fc\u30de\u30f3\u30c7\u30fc\u306f\u6765\u9031\uff12\uff17\u65e5\u6708\u66dc\u65e5\u3067\u3059\uff01\uff01"},"content":{"rendered":"

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5\u6642\u306b\u8d77\u304d\u3066\u671d\u4f1a\u306b\u884c\u304f\u4e88\u5b9a\u3067\u3057\u305f\u304c\u3001\u305d\u308c\u3069\u3053\u308d\u3067\u306f\u306a\u304b\u3063\u305f\u3067\u3059\u3002<\/p>\n

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\u3055\u3066\u3001<\/p>\n

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\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb
\n\u30e2\u30ea\u30f3\u30c0 \u30ef\u30fc\u30eb\u30c9\u30ef\u30a4\u30c9 \u30a4\u30f3\u30af(\u4ee5\u4e0b\u3001\u30e2\u30ea\u30f3\u30c0)\u3010\u672c\u793e\uff1a\u7c73\u56fd\u30e6\u30bf\u5dde\u30a2\u30e1\u30ea\u30ab\u30f3\u30d5\u30a9\u30fc\u30af\u3001\u793e\u9577\uff1a\u30b1\u30a2\u30ea\u30fc\u30fb\u30a8\u30a4\u30b7\u30fc\u3011\u306f\u3001\u540c\u5fd7\u793e\u5927\u5b66 \u751f\u547d\u533b\u79d1\u5b66\u90e8 \u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u30ea\u30b5\u30fc\u30c1\u30bb\u30f3\u30bf\u30fc \u7c73\u4e95\u5609\u4e00 \u6559\u6388\u3001\u516b\u6728\u96c5\u4e4b \u6559\u6388\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u8001\u5316\u306e\u539f\u56e0\u7269\u8cea\u3067\u3042\u308bAGE(\u7d42\u672b\u7cd6\u5316\u7523\u7269\uff0fAdvanced Glycation End products)\u3068\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u95a2\u4e0e\u306b\u3064\u3044\u3066\u300111\u670817\u65e5\u306b\u958b\u50ac\u3055\u308c\u305f\u7b2c14\u56de \u7cd6\u5316\u30b9\u30c8\u30ec\u30b9\u7814\u7a76\u4f1a\u306e\u8b1b\u6f14\u4f1a\u306b\u304a\u3044\u3066\u767a\u8868\u3057\u307e\u3057\u305f\u3002
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\u3010\u7814\u7a76\u6982\u8981\u3011
\n\u25a0\u80cc\u666f\u30fb\u76ee\u7684
\n\u8102\u8cea\u7570\u5e38\u75c7\u306f\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u767a\u751f\u3001\u9032\u884c\u306e\u4e3b\u8981\u306a\u539f\u56e0\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u306a\u304b\u3067\u3082\u3001\u9ad8LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306f\u9178\u5316\u30fb\u5909\u6027\u306b\u3088\u308a\u52d5\u8108\u786c\u5316\u3092\u5f15\u304d\u8d77\u3053\u3057\u5faa\u74b0\u5668\u7cfb\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3002\u5148\u884c\u7814\u7a76\u306b\u3088\u308a\u3001\u9ad8LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306e\u4e00\u56e0\u306bLDL\u306e\u7cd6\u5316\u304c\u3042\u308a\u3001\u7cd6\u5316\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001LDL\u5024\u304c\u4e0b\u304c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b1)\u3002
\n\u305d\u3053\u3067\u672c\u7814\u7a76\u3067\u306f\u3001AGE\u751f\u6210\u963b\u5bb3\u4f5c\u7528\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u30a4\u30ea\u30c9\u30a4\u30c9\u542b\u6709\u690d\u72692)\u306eLDL\u7cd6\u5316\u6291\u5236\u4f5c\u7528\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u305f\u3002<\/p>\n

\u25a0\u65b9\u6cd5
\nLDL\u3068\u30b0\u30ea\u30bb\u30eb\u30a2\u30eb\u30c7\u30d2\u30c9\u3092in vitro(\u8a66\u9a13\u7ba1\u5185)\u306b\u30662\u65e5\u9593\u53cd\u5fdc\u3055\u305b\u3001AGE\u751f\u6210\u91cf\u3092\u78ba\u8a8d\u3057\u305f\u3002\u6b21\u306b\u3001\u3059\u3067\u306bAGEs\u751f\u6210\u6291\u5236\u4f5c\u7528\u3092\u6301\u3064\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u30a4\u30ea\u30c9\u30a4\u30c9\u542b\u6709\u690d\u7269\u3067\u3042\u308b\u30ce\u30cb(Morinda citrifolia)\u3001\u30b5\u30f3\u30b7\u30e5\u30e6(Cornus officinalis)\u304a\u3088\u3073\u30aa\u30ea\u30fc\u30d6(Olea europaea)\u306eAGE-LDL\u751f\u6210\u6291\u5236\u4f5c\u7528\u3092\u30a2\u30df\u30ce\u30b0\u30a2\u30cb\u30b8\u30f3(AG\uff1a\u6297\u7cd6\u5316\u7269\u8cea)\u3068\u6bd4\u8f03\u3057\u3001\u691c\u8a0e\u3057\u305f\u3002<\/p>\n

\u25a0\u7d50\u679c
\nLDL\u3068\u30b0\u30ea\u30bb\u30eb\u30a2\u30eb\u30c7\u30d2\u30c9\u3092in vitro\u306b\u3066\u53cd\u5fdc\u3055\u305b\u305f\u3068\u3053\u308d\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u6bd4\u8f03\u3057\u7d04500\u500d\u306eAGE\u3092\u751f\u6210\u3057\u3001\u6709\u610f\u5dee\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u3053\u306eAGE-LDL\u3092\u7528\u3044\u3066\u30a4\u30ea\u30c9\u30a4\u30c9\u542b\u6709\u88ab\u691c\u4f53\u3092\u691c\u8a0e\u3057\u305f\u7d50\u679c\u3001200\u03bcg\/ml\u6fc3\u5ea6\u306b\u304a\u3044\u3066\u3001\u30b5\u30f3\u30b7\u30e5\u30e6\u679c\u5b9f\u30a8\u30ad\u30b9(\u963b\u5bb3\u738775.8\uff05)\u3001\u30ce\u30cb\u7a2e\u5b50\u30a8\u30ad\u30b9(35.2\uff05)\u3001\u30ce\u30cb\u8449\u30a8\u30ad\u30b9(31.5\uff05)\u3001\u30aa\u30ea\u30fc\u30d6\u8449\u30a8\u30ad\u30b9(27.3\uff05)\u306b\u6291\u5236\u4f5c\u7528\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u30b5\u30f3\u30b7\u30e5\u30e6\u679c\u5b9f\u306e\u963b\u5bb3\u4f5c\u7528\u306f\u3001\u30a2\u30df\u30ce\u30b0\u30a2\u30cb\u30b8\u30f3\u3088\u308a\u3082\u5f37\u3044\u3082\u306e\u3067\u3042\u3063\u305f\u3002\u3088\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u30a4\u30ea\u30c9\u30a4\u30c9\u542b\u6709\u690d\u7269\u306f\u3001AGE-LDL\u751f\u6210\u6291\u5236\u4f5c\u7528\u3082\u6301\u3061\u5408\u308f\u305b\u308b\u6297AGE\u690d\u7269\u7d20\u6750\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3002<\/p>\n

AGE-LDL\u751f\u6210\u6291\u5236\u4f5c\u7528<\/p>\n

MCF\uff1a\u30ce\u30cb\u679c\u5b9f\u3001MCL\uff1a\u30ce\u30cb\u8449\u3001MCS\uff1a\u30ce\u30cb\u7a2e\u5b50\u3001COF\uff1a\u30b5\u30f3\u30b7\u30e5\u30e6\u679c\u5b9f\u3001OEL\uff1a\u30aa\u30ea\u30fc\u30d6\u8449\u3001AG\uff1a\u30a2\u30df\u30ce\u30b0\u30a2\u30cb\u30b8\u30f3<\/p>\n

\u53c2\u7167\u6587\u732e\uff1a1) Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9441-5.
\n\u3000\u3000\u3000\u3000\u30002) Glycative Stress Research 2016 3(2): 56-64.<\/p>\n

\u3010AGE(\u7d42\u672b\u7cd6\u5316\u7523\u7269)\u3068\u306f\u3011
\nAGE\u3068\u306f\u7d42\u672b\u7cd6\u5316\u7523\u7269(Advanced Glycation End Products)\u3001\u3059\u306a\u308f\u3061\u300c\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u7cd6\u304c\u52a0\u71b1\u3055\u308c\u3066\u3067\u304d\u305f\u7269\u8cea\u300d\u306e\u3053\u3068\u3002\u8001\u5316\u3092\u9032\u3081\u308b\u539f\u56e0\u7269\u8cea\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3010\u30e2\u30ea\u30f3\u30c0 \u30ef\u30fc\u30eb\u30c9\u30ef\u30a4\u30c9 \u30a4\u30f3\u30af\u306b\u3064\u3044\u3066\u3011
\n\u30e2\u30ea\u30f3\u30c0 \u30a4\u30f3\u30af(\u672c\u793e\uff1a\u7c73\u56fd\u30e6\u30bf\u5dde\u30a2\u30e1\u30ea\u30ab\u30f3\u30d5\u30a9\u30fc\u30af\u30011996\u5e74\u5275\u696d)\u306f\u3001\u300c\u30ce\u30cb(\u5b66\u540d\uff1a\u30e2\u30ea\u30f3\u30c0\u30b7\u30c8\u30ea\u30d5\u30a9\u30ea\u30a2)\u300d\u306e\u5065\u5eb7\u3078\u306e\u6075\u307f\u3092\u4e16\u754c\u306b\u521d\u3081\u3066\u7d39\u4ecb\u3057\u305f\u7814\u7a76\u4e3b\u5c0e\u578b\u4f01\u696d\u3067\u3059\u3002\u4e16\u754c\u4e2d\u306e\u4eba\u3005\u304c\u3088\u308a\u5065\u5eb7\u3067\u751f\u304d\u751f\u304d\u3068\u3057\u305f\u751f\u6d3b\u3092\u304a\u304f\u308c\u308b\u3088\u3046\u3001\u30ce\u30cb\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u6709\u7528\u690d\u7269\u3092\u4e16\u754c\u4e2d\u304b\u3089\u53b3\u9078\u3057\u3001\u5065\u5eb7\u30fb\u7f8e\u5bb9\u95a2\u9023\u88fd\u54c1\u306e\u7814\u7a76\u30fb\u958b\u767a\u30fb\u88fd\u9020\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u30e2\u30ea\u30f3\u30c0 \u30ef\u30fc\u30eb\u30c9\u30ef\u30a4\u30c9 \u30a4\u30f3\u30af\u306f\u3001\u30e2\u30ea\u30f3\u30c0 \u30a4\u30f3\u30af\u306e\u88fd\u9020\u3059\u308b\u88fd\u54c1\u306e\u8f38\u51fa\u5165\u30fb\u8ca9\u58f2\u696d\u52d9\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u8a73\u7d30\u306f http:\/\/morinda.com \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n

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\u3044\u3064\u3082\u601d\u3044\u307e\u3059\u304c\u3001\u30e2\u30ea\u30f3\u30c0\u793e\u306f\u5065\u5eb7\u7523\u696d\u306e\u6700\u524d\u7dda\u3092\u8d70\u3063\u3066\u3044\u307e\u3059\u306d\u3002<\/p>\n

\u8208\u5473\u6df1\u3044\u8ad6\u6587\u3067\u3057\u305f\u3002<\/p>\n

\u3053\u308c\u304b\u3089\u3082\u697d\u3057\u307f\u3067\u3059\u3002<\/p>\n

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\"\"<\/a><\/p>\n

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